One of the most common OCE methods relies on quantifying the properties of elastic waves in tissues. Mechanical properties such as Young’s modulus and shear viscosity can be estimated from the speed, dispersion, damping, and other properties of the elastic wave. The GIBIO Research Group has successfully utilized wave-based OCE to study the biomechanical properties of numerous tissues, such as the cornea, iris, limbus, sclera, skin, colon, kidneys, cardiovascular tissues, and connective tissues. These waves can be excited by a variety of methods tailored to the specific application. For example, acoustic radiation force stimulation can excite mechanical waves in tissues noninvasively.
